The layout of the Microlino will change little from that of the Isetta: There is a single bench up front for a driver and a passenger, along with a steering wheel and instrument panel incorporated into the front door that opens refrigerator-style. The rear door, which opens upward, offers a modest cargo area, while the battery is under the floor. The headlights are in pods that double as sideview mirrors in another nod to the original Isetta.
Will you be able to buy one in the U.S.? The company plans to offer the Microlino in Europe and license its production, but it hasn't mentioned plans for U.S. sales. Because of its limited speed and, ahem, design-limited crash safety potential, licensing for the road is unlikely but it may (in theory) still be registered as a low-speed EV not meant for public roads, depending on the state.
Ultimately, there is no way to make a modernized Isetta comply with federal crash safety regulations short of adding a hood and making the whole thing Smart EV-sized, at which point it'll cease to be an Isetta.
We have an easier time picturing the Microlino sharing road space with dozens of Vespa scooters in a quaint Italian village in the Alps or finding a parking spot along the canals of Amsterdam than being subjected to the horrors of Los Angeles traffic or competing for space with trucks doing 80 mph on the Pennsylvania Turnpike.